Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12462194 | 0.85 | TSHR (0.51) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4138562 | 0.84 | TSHR (0.48) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1753633 | 0.84 | TSHR (0.53) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL20117523 | 0.84 | TSHR (0.50) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL429195 | 0.83 | TSHR (0.49) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL20365712 | 0.82 | TSHR (0.46) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL410889 | 0.82 | TSHR (0.46) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL17658797 | 0.82 | TSHR (0.54) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13647776 | 0.82 | TSHR (0.68) | TSHRMAPTALDH1A1 | |
| SCHEMBL1753863 | 0.81 | TSHR (0.56) | TSHRMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637589-B2 | Silicone prepolymer solutions | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-8399539-B2 | Soluble silicone prepolymers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-20120065348-A1 | SOLUBLE SILICONE PREPOLYMERS | TORAY INDUSTRIES, INC. (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20110077322-A1 | Silicone Prepolymer Solutions | TORAY INDUSTRIES, INC. (JP) | 2011-03-31 | — | — | US | disclosed |