Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.53 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.53 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049612 | 0.86 | MEN1 (0.55) | ESR2SMARCA2SMARCA4PBRM1LMNA | |
| SCHEMBL12516958 | 0.86 | SMARCA2 (0.57) | ESR2SMARCA2SMARCA4PBRM1LMNA | |
| SCHEMBL8259574 | 0.86 | ESR2 (0.52) | ESR2SMARCA2SMARCA4PBRM1LMNA | |
| SCHEMBL6773498 | 0.85 | ESR2 (0.51) | ESR2SMARCA2SMARCA4PBRM1LMNA | |
| SCHEMBL24309718 | 0.84 | ESR2 (0.53) | ESR2SMARCA2SMARCA4PBRM1LMNA | |
| SCHEMBL5543104 | 0.84 | ESR2 (0.56) | ESR2SMARCA2SMARCA4PBRM1LMNA | |
| SCHEMBL29566479 | 0.84 | ESR2 (0.56) | ESR2SMARCA2SMARCA4PBRM1LMNA | |
| SCHEMBL4951947 | 0.83 | ESR2 (0.52) | ESR2SMARCA2SMARCA4PBRM1LMNA | |
| SCHEMBL30221986 | 0.83 | ESR2 (0.52) | ESR2SMARCA2SMARCA4PBRM1LMNA | |
| SCHEMBL2382922 | 0.82 | GAA (0.69) | SMARCA2SMARCA4PBRM1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016051799-A1 | 2-AMINOHYDROQUINONE DERIVATIVE AND TAU AGGREGATION INHIBITOR | 学校法人同志社 | 2016-04-07 | — | — | WO | disclosed |