Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.48 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951947 | 1.00 | ESR2 (0.52) | ESR2L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL8259574 | 0.89 | ESR2 (0.52) | ESR2L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL22532774 | 0.88 | SMN1; SMN2 (0.56) | L3MBTL1MAPTMEN1KMT2AGPR119 | |
| SCHEMBL3929365 | 0.86 | L3MBTL1 (0.55) | L3MBTL1MAPTMEN1KMT2AGPR119 | |
| SCHEMBL1907784 | 0.85 | CYP3A4 (0.56) | L3MBTL1MAPTMEN1KMT2AGPR119 | |
| SCHEMBL29508938 | 0.85 | NR1H2 (0.53) | L3MBTL1MAPTMEN1KMT2AGPR119 | |
| SCHEMBL660403 | 0.85 | NR1H2 (0.53) | L3MBTL1MAPTMEN1KMT2AGPR119 | |
| SCHEMBL29197465 | 0.85 | L3MBTL1 (0.51) | L3MBTL1MAPTMEN1KMT2AGPR119 | |
| SCHEMBL7123953 | 0.85 | BACE1 (0.54) | L3MBTL1MAPTMEN1KMT2AGPR119 | |
| SCHEMBL30591201 | 0.85 | CYP3A4 (0.56) | L3MBTL1MAPTMEN1KMT2AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991679-A | 2-oxothiazole derivatives as A2A inhibitors and compounds for the treatment of cancer | 伊忒欧斯比利时股份公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115873022-A | 2-oxothiazole derivatives as A2A inhibitors and compounds for the treatment of cancer | 伊忒欧斯比利时股份公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-110678472-B | 2-oxothiazole derivatives as A2A inhibitors and compounds for the treatment of cancer | 伊忒欧斯比利时股份公司 | 2023-01-24 | — | — | CN | disclosed |