Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | CDK11B | P21127 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | CDKL2 | Q92772 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17658745 | 0.88 | MPO (0.37) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL12336300 | 0.82 | PDGFRB (0.55) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL626064 | 0.75 | PDGFRB (0.53) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL12336281 | 0.75 | PDGFRB (0.51) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL12336580 | 0.74 | MAPT (0.47) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL14949595 | 0.74 | PDGFRB (0.53) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL14949586 | 0.73 | PDGFRB (0.53) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL17661839 | 0.73 | PDGFRB (0.55) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL12336283 | 0.73 | PDGFRB (0.56) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL14949696 | 0.72 | PDGFRB (0.41) | PDGFRBKITPDGFRACDK11BFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160096824-A1 | Heterocyclic Compounds Useful for Kinase Inhibition | AMITECH THERAPEUTIC SOLUTIONS, INC. | 2016-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096824-A1 | Heterocyclic Compounds Useful for Kinase Inhibition | MAP4K2, MAP3K20, MAP3K19 | PDGFRB 497/4885KIT 540/4885PDGFRA 498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.