Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 19/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 11/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17664347 | 0.83 | S1PR3 (0.71) | S1PR3S1PR4S1PR1S1PR5S1PR2 | |
| SCHEMBL17664437 | 0.82 | S1PR3 (0.69) | S1PR3S1PR4S1PR1S1PR5S1PR2 | |
| SCHEMBL17664421 | 0.73 | S1PR3 (0.52) | S1PR3S1PR4S1PR1S1PR5S1PR2 | |
| SCHEMBL17663900 | 0.70 | S1PR3 (0.60) | S1PR3S1PR4S1PR1S1PR5 | |
| SCHEMBL17663930 | 0.68 | S1PR3 (0.47) | S1PR3S1PR4S1PR1S1PR2 | |
| SCHEMBL23715847 | 0.67 | S1PR3 (0.42) | S1PR3S1PR4S1PR1S1PR5S1PR2 | |
| SCHEMBL17663954 | 0.66 | S1PR3 (0.82) | S1PR3S1PR4S1PR1S1PR5S1PR2 | |
| SCHEMBL17663950 | 0.66 | S1PR3 (0.91) | S1PR3S1PR4S1PR1S1PR5S1PR2 | |
| SCHEMBL6072225 | 0.65 | GRM4 (0.65) | KDM4C | |
| SCHEMBL178048 | 0.65 | KDM4C (0.75) | KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016053855-A1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-04-07 | — | — | WO | disclosed |