Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 4/20 | 0.59 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.57 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.55 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15901016 | 0.88 | NPC1 (0.63) | GRM4HDAC6NPC1RAB9AMEN1 | |
| SCHEMBL14953564 | 0.87 | JAK2 (0.60) | GRM4HDAC6NPC1RAB9AMEN1 | |
| SCHEMBL1938787 | 0.86 | CNR2 (0.65) | GRM4HDAC6NPC1RAB9AMEN1 | |
| SCHEMBL1938750 | 0.84 | GRM4 (0.55) | GRM4HDAC6RAB9AMEN1KMT2A | |
| SCHEMBL27847068 | 0.83 | CCNC (0.62) | GRM4HDAC6NPC1RAB9AANO1 | |
| SCHEMBL15238558 | 0.82 | KDM4E (0.59) | GRM4HDAC6NPC1RAB9AANO1 | |
| SCHEMBL15691400 | 0.82 | KDR (0.58) | GRM4HDAC6NPC1RAB9AMEN1 | |
| SCHEMBL231897 | 0.80 | KDR (0.78) | GRM4HDAC6NPC1RAB9AKMT2A | |
| SCHEMBL1938862 | 0.80 | KMO (0.70) | GRM4HDAC6NPC1RAB9AMEN1 | |
| SCHEMBL5498068 | 0.80 | KMT2A (0.63) | GRM4HDAC6NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | ADAMS JERRY L | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | CHKB, MAP3K20, MAP3K6 | GRM4 3738/4885HDAC6 1597/4885NPC1 547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.