⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482656 | 0.90 | — | — | |
| SCHEMBL9164829 | 0.88 | FAAH (0.35) | — | |
| SCHEMBL3085457 | 0.79 | — | — | |
| SCHEMBL14025084 | 0.78 | — | — | |
| SCHEMBL14775481 | 0.76 | APEX1 (0.32) | — | |
| SCHEMBL12136466 | 0.73 | — | — | |
| SCHEMBL912621 | 0.71 | — | — | |
| SCHEMBL776623 | 0.71 | — | — | |
| SCHEMBL34460541 | 0.71 | — | — | |
| SCHEMBL14814314 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306115-A1 | Midazole-4-Carboxamide Derivatives For Use As Cb1 Modulators | ASTRAZENECA AB (SE) | 2008-12-11 | — | — | US | claimed |
| US-20080287517-A1 | Pyrazole Derivatives as Cb1 Modulators | ASTRAZENECA AB (SE) | 2008-11-20 | — | — | US | claimed |
| CN-101263134-A | Imidazole-4-carboxamide derivatives as CB modulators | ASTRAZENECA AB (SE) | 2008-09-10 | — | — | CN | claimed |
| CN-101223159-A | Pyrazole derivatives as CBI modulators | ASTRAZENECA AB (SE) | 2008-07-16 | — | — | CN | claimed |
| EP-1940820-A1 | MIDAZOLE-4-CARBOXAMIDE DERIVATIVES FOR USE AS CB MODULATORS | AstraZeneca AB (SE) | 2008-07-09 | — | — | EP | claimed |
| EP-1910331-A1 | PYRAZOLE DERIVATIVES AS CBl MODULATORS | AstraZeneca AB (SE) | 2008-04-16 | — | — | EP | claimed |
| WO-2007031721-A1 | MIDAZOLE-4-CARBOXAMIDE DERIVATIVES FOR USE AS CB MODULATORS | ASTRAZENECA AB (SE) | 2007-03-22 | — | — | WO | claimed |
| WO-2007010217-A1 | PYRAZOLE DERIVATIVES AS CBl MODULATORS | ASTRAZENECA AB (SE) | 2007-01-25 | — | — | WO | claimed |
| WO-2021153720-A1 | 3-ALKOXY BENZOIC ACID AMIDE DERIVATIVE, AND PEST CONTROL AGENT | クミアイ化学工業株式会社 | 2021-08-05 | — | — | WO | disclosed |
| EP-3081552-B1 | PEST CONTROL AGENT CONTAINING AN AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT | MITSUI CHEMICALS AGRO INC (JP) | 2021-03-03 | — | — | EP | disclosed |
| US-10582708-B2 | Amide derivative, pest control agent containing the amide derivative, and use of the amide derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2020-03-10 | — | — | US | disclosed |
| EP-2325165-B1 | AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND PEST CONTROLLING METHOD | MITSUI CHEMICALS AGRO INC (JP) | 2020-02-19 | — | — | EP | disclosed |
| US-20170367329-A1 | AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2017-12-28 | — | — | US | disclosed |
| US-9756856-B2 | Amide derivative, pest control agent containing the amide derivative, and use of the amide derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2017-09-12 | — | — | US | disclosed |
| CN-1109466-A | Hydrazone derivatives, processes for production thereof, and uses thereof | NIHON NOHYAKU CO LTD (JP) | 1995-10-04 | — | — | CN | disclosed |
| EP-0486937-B1 | Hydrazone derivatives, processes for production thereof, and uses thereof | NIHON NOHYAKU CO LTD (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-5358965-A | Agricultural and horticultural insecticides, activity against moths and beetles | NIHON NOHYAKU CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| US-5304573-A | Insecticides | NIHON NOHYAKU CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| CN-1061774-A | Hydrazone derivatives, process for producing the same and use thereof | NIHON NOHYAKU CO LTD (JP) | 1992-06-10 | — | — | CN | disclosed |
| EP-0486937-A1 | Hydrazone derivatives, processes for production thereof, and uses thereof | NIHON NOHYAKU CO., LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |