Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10042458 | 0.85 | ALDH1A1 (0.47) | ALDH1A1TDP1LMNA | |
| SCHEMBL11986884 | 0.84 | CA12 (0.41) | CA12CA9CA2ALDH1A1HPGD | |
| SCHEMBL1224664 | 0.83 | ALDH1A1 (0.56) | CA12CA9CA2ALDH1A1HPGD | |
| SCHEMBL25594540 | 0.83 | ALDH1A1 (0.36) | ALDH1A1TDP1LMNA | |
| SCHEMBL8045363 | 0.83 | ALDH1A1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL23054328 | 0.83 | ALDH1A1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL17448294 | 0.83 | TDP1 (0.36) | CA12CA9CA2ALDH1A1TSHR | |
| SCHEMBL5080836 | 0.82 | CA12 (0.43) | CA12CA9CA2ALDH1A1HPGD | |
| SCHEMBL19903149 | 0.81 | ALDH1A1 (0.43) | CA12CA9ALDH1A1TDP1CA1 | |
| SCHEMBL11425675 | 0.81 | CA12 (0.46) | CA12CA9CA2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021109351-A1 | POLYETHYLENE GLYCOL CONJUGATE DRUG, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-10 | — | — | WO | disclosed |
| WO-2021035310-A1 | TARGETED DENDRIMER CONJUGATES | STARPHARMA PTY LTD (AU) | 2021-03-04 | — | — | WO | disclosed |
| WO-2016050209-A1 | HETEROFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE, PREPARATION METHOD, AND BIO-RELATED SUBSTANCE | 厦门赛诺邦格生物科技有限公司 | 2016-04-07 | — | — | WO | disclosed |