SCHEMBL17664809

SCHEMBL17664809

CCOCC(COCC)OS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
GAA P10253 3/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
KMT2A Q03164 2/20 0.38
AGER Q15109 1/20 0.38
DHODH Q02127 1/20 0.37
CA12 O43570 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
VDR P11473 1/20 0.37
CA1 P00915 1/20 0.37
CA3 P07451 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37
CA5B Q9Y2D0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30831677 0.94 STAT3 (0.36) ALDH1A1GAAKDM4EHPGDCYP3A4
SCHEMBL30831592 0.87 PLA2G2C (0.37) ALDH1A1GAAKDM4EHPGDKMT2A
SCHEMBL16344580 0.85 ALDH1A1 (0.40) ALDH1A1GAAKDM4EHPGDCYP3A4
SCHEMBL13207910 0.84 CA12 (0.35) ALDH1A1GAAKDM4EHPGDCYP3A4
SCHEMBL13207907 0.84 CA12 (0.35) ALDH1A1GAAKDM4EHPGDCYP3A4
SCHEMBL11302375 0.83 PLA2G2C (0.54) ALDH1A1KDM4EHPGDCYP3A4CYP2C9
SCHEMBL10915388 0.83 PLA2G2C (0.54) ALDH1A1KDM4EHPGDCYP3A4CYP2C9
SCHEMBL2058187 0.83 GAA (0.42) ALDH1A1GAACYP3A4CYP2C9CYP2C19
SCHEMBL1192851 0.83 ALDH1A1 (0.44) ALDH1A1GAAHPGDCYP3A4CYP2C9
SCHEMBL16371958 0.83 ALDH1A1 (0.42) ALDH1A1GAAKDM4EHPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016050209-A1 HETEROFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE, PREPARATION METHOD, AND BIO-RELATED SUBSTANCE 厦门赛诺邦格生物科技有限公司 2016-04-07 WO disclosed