Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200596 | 0.79 | TSHR (0.38) | LMNATSHRL3MBTL1CYP1A2POLB | |
| SCHEMBL1482928 | 0.78 | — | — | |
| SCHEMBL18500437 | 0.75 | TSHR (0.36) | LMNATSHRL3MBTL1CYP1A2POLB | |
| Ethylene Glycol SCHEMBL356222 | 0.75 | LMNA (0.75) | LMNATSHRALDH1A1 | |
| SCHEMBL19227373 | 0.74 | TSHR (0.33) | LMNATSHRL3MBTL1CYP1A2POLB | |
| SCHEMBL10434124 | 0.74 | LMNA (0.57) | LMNATSHRALDH1A1SMN1; SMN2 | |
| Propanol SCHEMBL8131034 | 0.73 | LMNA (0.71) | LMNATSHRALDH1A1SMN1; SMN2 | |
| Alcohol SCHEMBL1490179 | 0.72 | LMNA (0.80) | LMNATSHRALDH1A1 | |
| SCHEMBL3453066 | 0.72 | — | — | |
| SCHEMBL18500371 | 0.72 | TSHR (0.34) | LMNATSHRL3MBTL1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016050209-A1 | HETEROFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE, PREPARATION METHOD, AND BIO-RELATED SUBSTANCE | 厦门赛诺邦格生物科技有限公司 | 2016-04-07 | — | — | WO | disclosed |