Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10280784 | 0.81 | ALDH1A1 (0.36) | ALDH1A1ALOX5APFEN1NPC1ATM | |
| SCHEMBL9952263 | 0.81 | POLB (0.39) | LMNAALDH1A1TSHRMITFMAPK1 | |
| SCHEMBL15426393 | 0.79 | NPC1 (0.37) | LMNAALDH1A1TSHRMITFMAPK1 | |
| SCHEMBL16280478 | 0.77 | NPC1 (0.36) | LMNAALDH1A1TSHRMITFMAPK1 | |
| SCHEMBL17666806 | 0.77 | NR1I2 (0.32) | ALOX5APFEN1NPC1ATMNR1I2 | |
| SCHEMBL15411967 | 0.72 | POLB (0.49) | LMNAALDH1A1ALOX5APFEN1NPC1 | |
| SCHEMBL15426400 | 0.71 | PADI4 (0.36) | LMNAALDH1A1TSHRMITFMAPK1 | |
| SCHEMBL10280726 | 0.70 | ALOX5AP (0.35) | ALOX5APFEN1NPC1ATMMAPT | |
| SCHEMBL10280980 | 0.70 | POLB (0.37) | ALOX5APFEN1NPC1ATMNR1I2 | |
| SCHEMBL15412891 | 0.70 | POLB (0.41) | ALOX5APFEN1NPC1ATMNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006429-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL CO., LTD. (JP) | 2016-04-13 | — | — | EP | disclosed |