Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 8/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17667010 | 1.00 | RAB9A (0.69) | RAB9AALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL8234749 | 0.81 | RAB9A (0.62) | RAB9AALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL20212003 | 0.81 | RAB9A (0.62) | RAB9AALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL17667004 | 0.81 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL17667001 | 0.81 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL18285086 | 0.80 | NPC1 (0.61) | RAB9AALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL1067851 | 0.79 | TSHR (0.65) | RAB9AALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL17667008 | 0.79 | RAB9A (0.55) | RAB9AALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL17667005 | 0.79 | RAB9A (0.55) | RAB9AALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL17667053 | 0.78 | RAB9A (0.54) | RAB9AALDH1A1SMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160152607-A1 | MALEIC ACID DERIVATIVE, PRODUCTION METHOD FOR SAME, AND ANTI-CANCER COMPOSITION COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-06-02 | — | — | US | claimed |
| EP-3006428-A1 | NOVEL MALEIC ACID DERIVATIVE, PRODUCTION METHOD FOR SAME AND ANTI-CANCER COMPOSITION COMPRISING SAME | Medicinal Bioconvergence Research Center (KR) | 2016-04-13 | — | — | EP | claimed |
| US-20160152607-A1 | MALEIC ACID DERIVATIVE, PRODUCTION METHOD FOR SAME, AND ANTI-CANCER COMPOSITION COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-06-02 | — | — | US | disclosed |
| US-20160152607-A1 | MALEIC ACID DERIVATIVE, PRODUCTION METHOD FOR SAME, AND ANTI-CANCER COMPOSITION COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-06-02 | — | — | US | disclosed |
| US-20160152607-A1 | MALEIC ACID DERIVATIVE, PRODUCTION METHOD FOR SAME, AND ANTI-CANCER COMPOSITION COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-06-02 | — | — | US | disclosed |
| EP-3006428-A1 | NOVEL MALEIC ACID DERIVATIVE, PRODUCTION METHOD FOR SAME AND ANTI-CANCER COMPOSITION COMPRISING SAME | Medicinal Bioconvergence Research Center (KR) | 2016-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152607-A1 | MALEIC ACID DERIVATIVE, PRODUCTION METHOD FOR SAME, AND ANTI-CANCER COMPOSITION COMPRISING SAME | NR1H4, CBR1, NR1H2 | RAB9A 4015/4885ALDH1A1 460/4885SMN1; SMN2 3186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.