SCHEMBL17667121

SCHEMBL17667121

CC1(C)c2ccccc2-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc4c(c3)-c3c(c5ccccc5n3-c3ccc(-c5ccccc5)cc3)C4(C)C)cc21

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ IL1R1 P14778 1/20 0.31
▸ MEN1 O00255 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ HTT P42858 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17667113 0.98 IL1R1 (0.33) IL1R1MEN1ALDH1A1MAPTHTT
SCHEMBL17667140 0.97 — —
SCHEMBL17667130 0.97 PDK2 (0.31) IL1R1
SCHEMBL17667136 0.96 PDK2 (0.30) —
SCHEMBL17667127 0.95 IL1R1 (0.32) IL1R1MEN1ALDH1A1MAPTHTT
SCHEMBL17667119 0.93 PDK2 (0.30) IL1R1L3MBTL1
SCHEMBL17667134 0.91 PDK2 (0.31) —
SCHEMBL17677114 0.91 — —
SCHEMBL17667141 0.91 IL1R1 (0.37) IL1R1MEN1ALDH1A1MAPTHTT
SCHEMBL17677030 0.90 PDK2 (0.31) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3006426-B1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2019-01-09 — — EP disclosed
US-9985216-B2 Indenoindole derivative and organic electroluminescent element HODOGAYA CHEMICAL CO., LTD. (JP) 2018-05-29 — — US disclosed
US-20160126468-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO., LTD. (JP) 2016-05-05 — — US disclosed
EP-3006426-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2016-04-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160126468-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT IDO2, SLCO2B1, IDO1 IL1R1 2572/4885MEN1 1686/4885ALDH1A1 1025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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