SCHEMBL17667136

SCHEMBL17667136

CC1(C)c2ccccc2-c2ccc(N(c3ccccc3)c3ccc(-c4ccc5c(c4)-c4c(c6ccccc6n4-c4ccc(-c6ccccc6)cc4)C5(C)C)cc3)cc21

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17667130 0.99 PDK2 (0.31) PDK2
SCHEMBL17667119 0.97 PDK2 (0.30) PDK2
SCHEMBL17667127 0.97 IL1R1 (0.32) PDK2
SCHEMBL17667121 0.96 IL1R1 (0.31) —
SCHEMBL17667134 0.95 PDK2 (0.31) PDK2
SCHEMBL17667113 0.94 IL1R1 (0.33) —
SCHEMBL17667140 0.93 — —
SCHEMBL17667122 0.92 IL1R1 (0.34) —
SCHEMBL17667114 0.92 — —
SCHEMBL17677027 0.91 PDK2 (0.31) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3006426-B1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2019-01-09 — — EP disclosed
US-9985216-B2 Indenoindole derivative and organic electroluminescent element HODOGAYA CHEMICAL CO., LTD. (JP) 2018-05-29 — — US disclosed
US-20160126468-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO., LTD. (JP) 2016-05-05 — — US disclosed
EP-3006426-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2016-04-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160126468-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT IDO2, SLCO2B1, IDO1 PDK2 1509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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