Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17667814 | 0.91 | CSNK2A1 (0.42) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL17667816 | 0.89 | TRPV1 (0.46) | ALDH1A1MAPTKDM4EHPGDPOLB | |
| SCHEMBL4002255 | 0.88 | CSNK2A2 (0.47) | HSD17B10ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL3001735 | 0.87 | ALDH1A1 (0.55) | HSD17B10ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL4008540 | 0.86 | CSNK2A2 (0.48) | HSD17B10ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL3002368 | 0.86 | CSNK2A2 (0.48) | HSD17B10ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL3001522 | 0.84 | CSNK2A2 (0.48) | HSD17B10ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL3001985 | 0.84 | CSNK2A2 (0.43) | HSD17B10ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL3007864 | 0.82 | CSNK2A2 (0.47) | HSD17B10ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL17667808 | 0.82 | TRPV1 (0.52) | HPGDBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-B1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | MEDIFRON DBT CO LTD (KR) | 2016-04-13 | — | — | EP | claimed |