Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.83 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tak-441 SCHEMBL1061476 | 0.91 | SMO (1.00) | SMO | |
| SCHEMBL17667833 | 0.89 | SMO (0.80) | SMO | |
| SCHEMBL1062967 | 0.84 | SMO (0.87) | SMO | |
| SCHEMBL1062538 | 0.84 | SMO (0.87) | SMO | |
| SCHEMBL1058049 | 0.84 | SMO (0.86) | SMO | |
| SCHEMBL1062032 | 0.84 | SMO (0.59) | SMOADRA1DADRA1AADRA1BCARM1 | |
| SCHEMBL1057379 | 0.83 | SMO (0.83) | SMO | |
| SCHEMBL1060514 | 0.82 | SMO (0.85) | SMO | |
| SCHEMBL1062658 | 0.82 | SMO (0.68) | SMO | |
| SCHEMBL1059600 | 0.82 | SMO (0.84) | SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247588-B1 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2016-04-13 | — | — | EP | claimed |