Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | TPH1 | P17752 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321936 | 0.79 | ADORA2A (0.57) | ADORA2AADORA1ADORA2B | |
| SCHEMBL2326085 | 0.77 | ADORA2A (0.57) | ADORA2AADORA1ADORA2B | |
| SCHEMBL2320490 | 0.76 | ADORA2A (0.65) | ADORA2AADORA1ADORA2B | |
| SCHEMBL869894 | 0.72 | TPH1 (0.61) | TPH1 | |
| SCHEMBL869893 | 0.72 | TPH1 (0.61) | TPH1 | |
| SCHEMBL793094 | 0.71 | SLC7A5 (0.57) | — | |
| SCHEMBL793095 | 0.71 | SLC7A5 (0.57) | — | |
| SCHEMBL1802025 | 0.68 | PTPN1 (0.78) | TPH1 | |
| SCHEMBL18256435 | 0.68 | PTPN1 (0.78) | TPH1 | |
| SCHEMBL1802026 | 0.68 | PTPN1 (0.78) | TPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531492-B1 | 1,2,4-TRIAZINE-4-AMINE DERIVATIVES | HEPTARES THERAPEUTICS LTD (GB) | 2016-04-13 | — | — | EP | disclosed |