Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BID | P55957 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 3/20 | 0.42 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17669150 | 0.88 | RXFP1 (0.52) | HTTPPARALMNAALDH1A1PPARG | |
| SCHEMBL2944712 | 0.80 | PPARA (0.73) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL2945954 | 0.79 | PPARA (0.56) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL489605 | 0.78 | PPARA (0.55) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL2950017 | 0.78 | TRPV1 (0.47) | HTTLMNAALDH1A1RAB9A | |
| SCHEMBL2942158 | 0.76 | AR (0.43) | — | |
| SCHEMBL2950034 | 0.75 | AR (0.52) | HTTLMNAALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL13533513 | 0.75 | PPARA (0.68) | PPARALMNAALDH1A1PPARGSMN1; SMN2 | |
| SCHEMBL13533521 | 0.72 | PPARA (0.58) | HTTPPARALMNAALDH1A1PPARG | |
| SCHEMBL489762 | 0.69 | PPARA (0.46) | PPARAPPARGBIDMCL1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160101076-A1 | Use of Sumoylation Inhibitors for Treating Cancer | WEIGEL RONALD J (US) | 2016-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160101076-A1 | Use of Sumoylation Inhibitors for Treating Cancer | SUMO2, SUMO1, UBA2 | HTT 4360/4885PPARA 540/4885LMNA 3414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.