Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | EPOR | P19235 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL17669759 | 1.00 | CPB2 (0.41) | CPB2GSRRNPEPTPSAB1TPSD1 | |
| SCHEMBL2211497 | 0.98 | CPB2 (0.42) | CPB2GSRRNPEPTPSAB1TPSD1 | |
| SCHEMBL7416589 | 0.98 | CPB2 (0.42) | CPB2GSRRNPEPTPSAB1TPSD1 | |
| SCHEMBL1039473 | 0.98 | CPB2 (0.42) | CPB2GSRRNPEPTPSAB1TPSD1 | |
| SCHEMBL3662433 | 0.94 | CPB2 (0.40) | CPB2GSRRNPEPTPSAB1TPSD1 | |
| SCHEMBL1022347 | 0.94 | CPB2 (0.40) | CPB2GSRRNPEPTPSAB1TPSD1 | |
| SCHEMBL3662436 | 0.94 | CPB2 (0.40) | CPB2GSRRNPEPTPSAB1TPSD1 | |
| SCHEMBL6653557 | 0.88 | CPB2 (0.36) | CPB2GSRRNPEPMEN1GAA | |
| SCHEMBL17077602 | 0.88 | CPB2 (0.37) | CPB2GSRRNPEPTPSAB1TPSD1 | |
| SCHEMBL16862530 | 0.88 | GSR (0.38) | CPB2GSRRNPEPTPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9631044-B2 | Comb-like polyurethane and methods for preparing and using the same | SICHUAN UNIVERSITY (CN) | 2017-04-25 | — | — | US | disclosed |
| US-20160102167-A1 | COMB-LIKE POLYURETHANE AND METHODS FOR PREPARING AND USING THE SAME | LAVAL UNIVERSITY (CA) | 2016-04-14 | — | — | US | disclosed |