SCHEMBL17672298

SCHEMBL17672298

NC(=O)/C=C/C(=O)N1CCCCCCCCCC1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
PARP1 P09874 1/20 0.42
PARP15 Q460N3 1/20 0.42
PARP10 Q53GL7 1/20 0.42
MAPT P10636 2/20 0.41
ALOX5 P09917 2/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
HPGD P15428 1/20 0.41
F2 P00734 1/20 0.41
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18695009 0.88 MEN1 (0.38) ALDH1A1PARP1PARP15PARP10MAPT
SCHEMBL1832185 0.88 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2MAPTALOX5MEN1
SCHEMBL1832187 0.88 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2MAPTALOX5MEN1
SCHEMBL22622465 0.85 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2MAPTALOX5MEN1
SCHEMBL5446634 0.79 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2HPGDF2
SCHEMBL4021537 0.79 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2MAPTMEN1RAB9A
SCHEMBL4021544 0.79 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2MAPTMEN1RAB9A
SCHEMBL6651491 0.79 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2MAPTMEN1RAB9A
SCHEMBL21872351 0.76 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2MAPTALOX5MEN1
SCHEMBL14655445 0.76 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2PARP1PARP15PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10695462-B2 On-demand degradable medical devices YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2020-06-30 US claimed
US-20170312388-A1 ON-DEMAND DEGRADABLE MEDICAL DEVICES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2017-11-02 US claimed
EP-3204060-A1 ON-DEMAND DEGRADABLE MEDICAL DEVICES Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2017-08-16 EP claimed
WO-2016056008-A1 ON-DEMAND DEGRADABLE MEDICAL DEVICES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2016-04-14 WO claimed
US-11160935-B2 Reusable instrument handle with single-use tip KATALYST SURGICAL, LLC (US) 2021-11-02 US disclosed
US-10772676-B2 Microsurgical bipolar forceps Kogent Surgical, LLC (US) 2020-09-15 US disclosed
US-10709504-B2 Curved laser probe with single-use optic fiber KATALYST SURGICAL, LLC (US) 2020-07-14 US disclosed
US-10695462-B2 On-demand degradable medical devices YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2020-06-30 US disclosed
US-10646113-B2 Illuminated cannula KATALYST SURGICAL, LLC (US) 2020-05-12 US disclosed
EP-3373873-B1 LASER PROBE WITH REPLACEABLE OPTIC FIBERS KATALYST SURGICAL LLC (US) 2020-02-19 EP disclosed
EP-3478204-A1 REUSABLE LASER PROBE WITH SINGLE-USE OPTIC FIBER Katalyst Surgical, LLC (US) 2019-05-08 EP disclosed
EP-3471673-A1 REUSABLE INSTRUMENT HANDLE WITH SINGLE- USE TIP Katalyst Surgical, LLC (US) 2019-04-24 EP disclosed
US-20170312388-A1 ON-DEMAND DEGRADABLE MEDICAL DEVICES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2017-11-02 US disclosed
US-20170281411-A1 SINGLE-USE LASER PROBE WITH REUSABLE OPTIC FIBER FIXTURES KATALYST SURGICAL, LLC (US) 2017-10-05 US disclosed
EP-3204060-A1 ON-DEMAND DEGRADABLE MEDICAL DEVICES Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2017-08-16 EP disclosed
US-20170135859-A1 LASER PROBE WITH REPLACEABLE OPTIC FIBERS KATALYST SURGICAL, LLC (US) 2017-05-18 US disclosed
WO-2017083097-A1 LASER PROBE WITH REPLACEABLE OPTIC FIBERS KATALYST SURGICAL, LLC (US) 2017-05-18 WO disclosed
WO-2017066026-A1 INSTRUMENT HANDLE AND REPLACEABLE TIP KATALYST SURGICAL, LLC (US) 2017-04-20 WO disclosed
US-20170100114-A1 INSTRUMENT HANDLE AND REPLACEABLE TIP KATALYST SURGICAL, LLC (US) 2017-04-13 US disclosed
WO-2016056008-A1 ON-DEMAND DEGRADABLE MEDICAL DEVICES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2016-04-14 WO disclosed