Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17674264 | 0.90 | NTRK1 (0.56) | NTRK1NTRK3 | |
| SCHEMBL17674377 | 0.89 | NTRK1 (0.67) | NTRK1NTRK3 | |
| SCHEMBL17674277 | 0.88 | NTRK1 (0.52) | NTRK1NTRK3 | |
| SCHEMBL17674281 | 0.84 | NTRK1 (0.55) | NTRK1NTRK3 | |
| SCHEMBL17674320 | 0.83 | NTRK1 (0.56) | NTRK1NTRK3 | |
| SCHEMBL17674421 | 0.81 | NTRK1 (0.51) | NTRK1NTRK3 | |
| SCHEMBL17674295 | 0.80 | NTRK1 (0.67) | NTRK1NTRK3 | |
| SCHEMBL17674257 | 0.78 | NTRK1 (0.65) | NTRK1NTRK3 | |
| SCHEMBL17674418 | 0.78 | NTRK1 (0.53) | NTRK1NTRK3 | |
| SCHEMBL17674436 | 0.77 | NTRK1 (0.65) | NTRK1NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016054807-A1 | TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF | MERCK SHARP & DOHME CORP. (US) | 2016-04-14 | — | — | WO | claimed |
| WO-2016054807-A1 | TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF | MERCK SHARP & DOHME CORP. (US) | 2016-04-14 | — | — | WO | disclosed |