Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.68 |
| ▸ | EGFR | P00533 | 14/20 | 0.68 |
| ▸ | TEC | P42680 | 3/20 | 0.57 |
| ▸ | TXK | P42681 | 3/20 | 0.57 |
| ▸ | BLK | P51451 | 3/20 | 0.57 |
| ▸ | BMX | P51813 | 3/20 | 0.57 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.57 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.54 |
| ▸ | JAK3 | P52333 | 2/20 | 0.54 |
| ▸ | ITK | Q08881 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17675376 | 0.96 | BTK (0.69) | BTKEGFRTECTXKBLK | |
| SCHEMBL17675620 | 0.91 | BTK (0.64) | BTKEGFRTECTXKBLK | |
| SCHEMBL17675232 | 0.90 | BTK (0.64) | BTKEGFRTECTXKBLK | |
| SCHEMBL17675198 | 0.90 | BTK (0.65) | BTKEGFRTECTXKBLK | |
| SCHEMBL17675231 | 0.89 | BTK (0.70) | BTKEGFRTECTXKBLK | |
| SCHEMBL17675252 | 0.88 | BTK (0.75) | BTKEGFRTECTXKBLK | |
| SCHEMBL17683770 | 0.88 | BTK (0.65) | BTKEGFRTECTXKBLK | |
| SCHEMBL17683785 | 0.88 | BTK (0.65) | BTKEGFRTECTXKBLK | |
| SCHEMBL17675611 | 0.88 | BTK (0.68) | BTKEGFRTECTXKBLK | |
| SCHEMBL17675526 | 0.87 | BTK (0.79) | BTKEGFRTECTXKBLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016055982-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS | ACERTA PHARMA B.V. (NL) | 2016-04-14 | — | — | WO | claimed |