Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.72 |
| ▸ | RAB9A | P51151 | 11/20 | 0.72 |
| ▸ | PKM | P14618 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16604283 | 0.90 | NPC1 (0.76) | NPC1RAB9APKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL16594545 | 0.86 | NPC1 (0.70) | NPC1RAB9APKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL21349103 | 0.86 | NPC1 (0.70) | NPC1RAB9APKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL26293792 | 0.86 | NPC1 (0.70) | NPC1RAB9APKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL17065565 | 0.86 | NPC1 (0.89) | NPC1RAB9APKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL2176413 | 0.86 | NPC1 (0.89) | NPC1RAB9APKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL7900640 | 0.85 | NPC1 (0.68) | NPC1RAB9APKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL14082359 | 0.84 | NPC1 (0.71) | NPC1RAB9APKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL18216806 | 0.84 | NPC1 (0.67) | NPC1RAB9APKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL403600 | 0.81 | NPC1 (1.00) | NPC1RAB9APKMSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016055982-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS | ACERTA PHARMA B.V. (NL) | 2016-04-14 | — | — | WO | disclosed |