Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.39 |
| ▸ | PER2 | O15055 | 3/20 | 0.35 |
| ▸ | CRY1 | Q16526 | 3/20 | 0.35 |
| ▸ | CRY2 | Q49AN0 | 3/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13566136 | 0.82 | PSEN1 (0.41) | CYP19A1PER2CRY1CRY2PSEN1 | |
| SCHEMBL17676562 | 0.78 | CYP19A1 (0.40) | CYP19A1PER2CRY1CRY2PTGDR2 | |
| SCHEMBL12967282 | 0.74 | PER2 (0.35) | CYP19A1PER2CRY1CRY2PSEN1 | |
| SCHEMBL12937418 | 0.74 | PSEN1 (0.34) | PER2CRY1CRY2PSEN1PSEN2 | |
| SCHEMBL17553805 | 0.71 | PSEN1 (0.42) | CYP19A1PER2CRY1CRY2PSEN1 | |
| SCHEMBL20230849 | 0.71 | CYP19A1 (0.44) | CYP19A1PER2CRY1CRY2PSEN1 | |
| SCHEMBL15503127 | 0.70 | HRH4 (0.44) | CYP19A1PER2CRY1CRY2PSEN1 | |
| SCHEMBL2737239 | 0.70 | PSEN1 (0.41) | CYP19A1PER2CRY1CRY2PSEN1 | |
| SCHEMBL16918235 | 0.69 | CYP19A1 (0.38) | CYP19A1PER2CRY1CRY2PSEN1 | |
| SCHEMBL16918159 | 0.68 | CYP19A1 (0.45) | CYP19A1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309260-B2 | Inhibitors of hepatitis C virus | PRESIDIO PHARMACEUTICALS, INC. (US) | 2016-04-12 | — | — | US | disclosed |