Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 5/20 | 0.58 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 4/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10327065 | 1.00 | CREBBP (0.58) | CREBBPBRPF1KDM4EALDH1A1MAPT | |
| SCHEMBL24852604 | 0.85 | CREBBP (0.55) | CREBBPBRPF1KDM4EALDH1A1MAPT | |
| SCHEMBL24852624 | 0.85 | CREBBP (0.55) | CREBBPBRPF1KDM4EALDH1A1MAPT | |
| SCHEMBL24852622 | 0.85 | CREBBP (0.55) | CREBBPBRPF1KDM4EALDH1A1MAPT | |
| SCHEMBL22722359 | 0.81 | CREBBP (0.50) | CREBBPBRPF1KDM4EALDH1A1MAPT | |
| SCHEMBL28448324 | 0.81 | CREBBP (0.53) | CREBBPBRPF1KDM4EALDH1A1MAPT | |
| SCHEMBL14172475 | 0.78 | CREBBP (0.53) | CREBBPBRPF1KDM4EALDH1A1MAPT | |
| SCHEMBL13870695 | 0.75 | BRPF1 (0.44) | CREBBPBRPF1KDM4EALDH1A1MAPT | |
| SCHEMBL17169671 | 0.74 | TNKS2 (0.44) | CREBBPBRPF1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23615537 | 0.74 | CREBBP (0.59) | CREBBPBRPF1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438989-B1 | USE OF ASYMMETRIC HYDROGENATION CATALYST | TAKASAGO PERFUMERY CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |