Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.55 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | NPEPPS | P55786 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.45 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.45 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.44 |
| ▸ | ANPEP | P15144 | 6/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672354 | 1.00 | LMNA (0.64) | LMNAP2RX3P2RX4P2RX2ADORA2A | |
| SCHEMBL29672348 | 1.00 | LMNA (0.64) | LMNAP2RX3P2RX4P2RX2ADORA2A | |
| SCHEMBL18512597 | 0.92 | LMNA (0.62) | LMNAP2RX3P2RX4P2RX2ADORA2A | |
| SCHEMBL16203604 | 0.92 | LMNA (0.62) | LMNAP2RX3P2RX4P2RX2ADORA2A | |
| SCHEMBL13863569 | 0.91 | LMNA (0.75) | LMNAP2RX3P2RX4P2RX2ENPP1 | |
| SCHEMBL13084357 | 0.91 | LMNA (0.75) | LMNAP2RX3P2RX4P2RX2ENPP1 | |
| SCHEMBL14075778 | 0.91 | LMNA (0.75) | LMNAP2RX3P2RX4P2RX2ENPP1 | |
| SCHEMBL13046095 | 0.91 | LMNA (0.75) | LMNAP2RX3P2RX4P2RX2ENPP1 | |
| SCHEMBL13084426 | 0.87 | LMNA (0.59) | LMNAP2RX3P2RX4P2RX2ADORA2A | |
| SCHEMBL17032321 | 0.87 | LMNA (0.62) | LMNAP2RX3P2RX4P2RX2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771344-B1 | NUCLEOSIDE ANALOGUES FOR TREATING A VIRAL INFECTION, AND METHOD FOR EVALUATING THE SENSITIVITY TO SAID TREATMENT | UNIVERSITÉ PIERRE ET MARIE CURIE PARIS 6 (FR) | 2016-04-13 | — | — | EP | disclosed |