Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MPO | P05164 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13557965 | 0.83 | MYC (0.37) | MYCSMN1; SMN2MAPTRXFP1POLB | |
| SCHEMBL13557967 | 0.82 | RXFP1 (0.40) | SMN1; SMN2MAPTRXFP1POLBMEN1 | |
| SCHEMBL16372510 | 0.80 | MEN1 (0.35) | MYCSMN1; SMN2MAPTMPORECQL | |
| SCHEMBL13559054 | 0.78 | CYP2C9 (0.55) | MAPTRXFP1POLBMEN1KMT2A | |
| SCHEMBL17677289 | 0.78 | POLB (0.45) | MAPTRXFP1POLBMEN1KMT2A | |
| SCHEMBL13259624 | 0.78 | POLB (0.58) | MAPTRXFP1POLBMEN1KMT2A | |
| SCHEMBL13559047 | 0.77 | KMT2A (0.60) | MAPTRXFP1POLBMEN1KMT2A | |
| SCHEMBL13559050 | 0.77 | POLB (0.44) | MAPTRXFP1POLBMEN1KMT2A | |
| SCHEMBL518816 | 0.75 | ALDH1A1 (0.51) | MYCSMN1; SMN2POLBKMT2AALDH1A1 | |
| SCHEMBL13559107 | 0.75 | ALDH1A1 (0.53) | MAPTRXFP1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006031-A1 | PYRIDAZINONE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2016-04-13 | — | — | EP | disclosed |