Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17679379 | 0.87 | ALDH1A1 (0.40) | ALDH1A1CYP2C9CYP2C19CYP3A4SLC1A3 | |
| SCHEMBL17679369 | 0.84 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP2C19SLC1A3SLC1A2 | |
| SCHEMBL17679381 | 0.81 | RCE1 (0.39) | ALDH1A1CYP2C9CYP2C19SLC1A3SLC1A2 | |
| SCHEMBL17679382 | 0.81 | RCE1 (0.39) | ALDH1A1CYP2C9CYP2C19CYP3A4SLC1A3 | |
| SCHEMBL16308015 | 0.80 | MAOB (0.44) | CYP2C9CYP2C19SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL17679390 | 0.80 | RCE1 (0.50) | ALDH1A1CYP2C9CYP2C19CYP3A4SLC1A3 | |
| SCHEMBL16308018 | 0.78 | RCE1 (0.38) | ALDH1A1CYP2C9CYP2C19SLC1A3SLC1A2 | |
| SCHEMBL17679376 | 0.78 | KMT2A (0.50) | ALDH1A1CYP2C9CYP2C19CYP3A4SLC1A3 | |
| SCHEMBL17679383 | 0.77 | TSHR (0.41) | CYP2C9CYP2C19SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL18950049 | 0.77 | RCE1 (0.45) | ALDH1A1CYP2C9CYP2C19CYP3A4SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160101414-A1 | HIGHLY Z-SELECTIVE AND ENANTIOSELECTIVE RING OPENING/CROSS METATHESIS CATALYZED BY A RESOLVED STEREOGENIC-AT-RU COMPLEX | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160101414-A1 | HIGHLY Z-SELECTIVE AND ENANTIOSELECTIVE RING OPENING/CROSS METATHESIS CATALYZED BY A RESOLVED STEREOGENIC-AT-RU COMPLEX | ZFR, ZDHHC7, ORC3 | ALDH1A1 2483/4885CYP2C9 1085/4885CYP2C19 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.