Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 2/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.36 |
| ▸ | CHUK | O15111 | 8/20 | 0.33 |
| ▸ | IKBKB | O14920 | 7/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | CIT | O14578 | 5/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | AURKAIP1 | Q9NWT8 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16908237 | 0.89 | CCNK (0.44) | CCNKCDK12CHUKIKBKBPIK3C3 | |
| Acetic Acid SCHEMBL15646249 | 0.86 | CIT (0.40) | CCNKCDK12CHUKIKBKBINSR | |
| SCHEMBL16908342 | 0.78 | CHUK (0.44) | CCNKCDK12CHUKIKBKBINSR | |
| SCHEMBL15645111 | 0.74 | IKBKB (0.41) | CCNKCDK12CHUKIKBKBPIK3C3 | |
| SCHEMBL16908324 | 0.73 | CIT (0.42) | CCNKCDK12CHUKIKBKBINSR | |
| SCHEMBL19880896 | 0.73 | CHUK (0.34) | CCNKCDK12CHUKIKBKBINSR | |
| SCHEMBL15645163 | 0.73 | CHUK (0.44) | CCNKCDK12CHUKIKBKBINSR | |
| Acetic Acid SCHEMBL28045010 | 0.73 | CIT (0.44) | CCNKCDK12CHUKIKBKBINSR | |
| Hydrochloric Acid SCHEMBL16897121 | 0.72 | CIT (0.41) | CCNKCDK12CHUKIKBKBINSR | |
| SCHEMBL16908234 | 0.72 | IKBKB (0.45) | CHUKIKBKBCIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160102094-A1 | Azaquinazoline Inhibitors of Atypical Protein Kinase C | IGNYTA, INC. (US) | 2016-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160102094-A1 | Azaquinazoline Inhibitors of Atypical Protein Kinase C | PRKCQ, PRKCZ, PRKCE | CCNK 283/4885CDK12 744/4885CHUK 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.