Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930158 | 0.88 | LMNA (0.53) | CYP1A2LMNACYP3A4MAOACA1 | |
| Hydrochloric Acid SCHEMBL9901295 | 0.87 | LMNA (0.51) | CYP1A2LMNACYP3A4MAOACA1 | |
| SCHEMBL14829294 | 0.82 | PDGFRB (0.49) | PDGFRBPDGFRACYP1A2LMNACYP3A4 | |
| SCHEMBL31426903 | 0.81 | PDGFRB (0.55) | PDGFRBPDGFRACYP1A2LMNACYP3A4 | |
| SCHEMBL1965326 | 0.79 | CA1 (0.73) | CYP1A2LMNACYP3A4MAOACA1 | |
| SCHEMBL16351874 | 0.79 | CA1 (0.73) | CYP1A2LMNACYP3A4MAOACA1 | |
| SCHEMBL14815530 | 0.79 | PDGFRB (0.51) | PDGFRBPDGFRACYP1A2LMNACYP3A4 | |
| SCHEMBL6644481 | 0.78 | MKNK1 (0.64) | PDGFRBPDGFRACYP1A2LMNACYP3A4 | |
| SCHEMBL14815570 | 0.77 | KDM4E (0.52) | PDGFRBPDGFRACYP1A2LMNACYP3A4 | |
| SCHEMBL7226164 | 0.77 | PDGFRB (0.46) | PDGFRBPDGFRACYP1A2LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016054807-A1 | TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF | MERCK SHARP & DOHME CORP. (US) | 2016-04-14 | — | — | WO | disclosed |