Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19538868 | 0.80 | CA12 (0.46) | KDM4EALDH1A1HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL31072830 | 0.80 | CA12 (0.46) | KDM4EALDH1A1HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL20604864 | 0.79 | CA12 (0.45) | KDM4EALDH1A1HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL31471666 | 0.79 | CA12 (0.45) | KDM4EALDH1A1HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL19231292 | 0.77 | KDM4E (0.48) | KDM4EALDH1A1HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL7425637 | 0.77 | MAPT (0.48) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL19531681 | 0.77 | KDM4E (0.48) | KDM4EALDH1A1HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL12992243 | 0.77 | TDP1 (0.46) | KDM4EALDH1A1HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL5881804 | 0.76 | LMNA (0.49) | KDM4EHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7474444 | 0.75 | KDM4E (0.42) | MTNR1AMTNR1BKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016055028-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2016-04-14 | — | — | WO | disclosed |