Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13790164 | 0.91 | KDM4E (0.57) | ACHEKDM4EMAPK1HIF1APAOX | |
| SCHEMBL18526264 | 0.89 | KDM4E (0.70) | ACHEKDM4EMAPK1HIF1APAOX | |
| SCHEMBL12282205 | 0.89 | KDM4E (0.70) | ACHEKDM4EMAPK1HIF1APAOX | |
| SCHEMBL12282006 | 0.87 | KDM4E (0.65) | KDM4EMAPK1HIF1APAOXEPHX2 | |
| SCHEMBL19960761 | 0.87 | TSHR (0.55) | ACHEKDM4EMAPK1HIF1AEPHX2 | |
| SCHEMBL13403098 | 0.86 | ACHE (0.61) | ACHEEPHX2 | |
| SCHEMBL14483854 | 0.85 | KDM4E (0.64) | ACHEKDM4EMAPK1HIF1APAOX | |
| SCHEMBL346549 | 0.84 | ACHE (0.73) | ACHEKDM4EMAPK1HIF1AEPHX2 | |
| SCHEMBL17680389 | 0.83 | ACHE (0.47) | ACHEKDM4EMAPK1HIF1APAOX | |
| SCHEMBL15850528 | 0.83 | ACHE (0.56) | ACHEPAOXEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160102168-A1 | BIO-BASED DIISOCYANATE AND CHAIN EXTENDERS IN CRYSTALLINE SEGMENTED THERMOPLASTIC POLYESTER URETHANES | TRENT UNIVERSITY (CA) | 2016-04-14 | — | — | US | disclosed |