Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 19/20 | 0.68 |
| ▸ | BRD4 | O60885 | 14/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22368662 | 0.83 | CREBBP (0.47) | CREBBPBRD4 | |
| SCHEMBL17680218 | 0.81 | CREBBP (1.00) | CREBBPBRD4 | |
| SCHEMBL22368827 | 0.79 | CREBBP (0.48) | CREBBPBRD4 | |
| SCHEMBL17680931 | 0.78 | CREBBP (0.62) | CREBBPBRD4 | |
| SCHEMBL17680929 | 0.78 | CREBBP (0.62) | CREBBPBRD4 | |
| SCHEMBL22368700 | 0.76 | CREBBP (0.45) | CREBBPBRD4 | |
| SCHEMBL22369137 | 0.74 | CREBBP (0.76) | CREBBPBRD4 | |
| SCHEMBL9791471 | 0.72 | CREBBP (0.56) | CREBBPBRD4MEN1ALDH1A1KMT2A | |
| SCHEMBL17680970 | 0.70 | CREBBP (0.68) | CREBBPBRD4 | |
| SCHEMBL9336652 | 0.68 | CREBBP (0.51) | CREBBPBRD4MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016055028-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2016-04-14 | — | — | WO | disclosed |