Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 15/20 | 0.62 |
| ▸ | BRD4 | O60885 | 9/20 | 0.62 |
| ▸ | EP300 | Q09472 | 1/20 | 0.62 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17680931 | 1.00 | CREBBP (0.62) | CREBBPBRD4EP300BRPF1RAB9A | |
| SCHEMBL17680933 | 0.80 | CREBBP (0.66) | CREBBPBRD4EP300BRPF1GAA | |
| SCHEMBL17680932 | 0.78 | CREBBP (0.68) | CREBBPBRD4 | |
| SCHEMBL17680234 | 0.77 | CREBBP (1.00) | CREBBPBRD4EP300BRPF1 | |
| SCHEMBL4902318 | 0.77 | CREBBP (1.00) | CREBBPBRD4EP300BRPF1 | |
| SCHEMBL17680584 | 0.77 | CREBBP (1.00) | CREBBPBRD4EP300BRPF1 | |
| SCHEMBL13729295 | 0.77 | CREBBP (0.62) | CREBBPBRD4EP300BRPF1RAB9A | |
| SCHEMBL22368662 | 0.76 | CREBBP (0.47) | CREBBPBRD4EP300 | |
| SCHEMBL17680969 | 0.73 | CREBBP (0.74) | CREBBPBRD4RAB9A | |
| SCHEMBL22368827 | 0.73 | CREBBP (0.48) | CREBBPBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016055028-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2016-04-14 | — | — | WO | disclosed |
| US-20150147457-A1 | ISOTOPICALLY MODIFIED COMPOUNDS AND THEIR USE AS FOOD SUPPLEMENTS | BIOJIVA LLC | 2015-05-28 | — | — | US | disclosed |