Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 3/20 | 0.50 |
| ▸ | CDK1 | P06493 | 3/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.50 |
| ▸ | GSK3A | P49840 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 3/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.43 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 4/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17681581 | 1.00 | CCNB2 (0.50) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL17681579 | 0.87 | GCGR (0.51) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL30567312 | 0.85 | TERT (0.49) | ABCG2TERTTOP1CYCSENPP2 | |
| SCHEMBL8198888 | 0.84 | TERT (0.46) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL10614661 | 0.84 | TOP1 (0.56) | ABCG2TERTTOP1CYCSENPP2 | |
| SCHEMBL6535064 | 0.84 | TERT (0.46) | ABCG2TERTTOP1CYCSENPP2 | |
| SCHEMBL9231247 | 0.84 | TERT (0.48) | ABCG2TERTTOP1CYCSENPP2 | |
| SCHEMBL2342864 | 0.84 | ABCG2 (0.56) | ABCG2TERTTOP1CYCSENPP2 | |
| SCHEMBL2319605 | 0.84 | ABCG2 (0.56) | ABCG2TERTTOP1CYCSENPP2 | |
| SCHEMBL2318530 | 0.84 | ABCG2 (0.56) | ABCG2TERTTOP1CYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315510-B2 | Method and application of unsymmetrically meso-substituted porphyrins and chlorins for PDT | BIOLITEC PHARMA MARKETING LTD (MY) | 2016-04-19 | — | — | US | claimed |