Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 3/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17606910 | 0.95 | MAPT (0.50) | MAPTTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL29513054 | 0.95 | MAPT (0.50) | MAPTTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL29444117 | 0.84 | ALDH1A1 (0.41) | MAPTTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL29822698 | 0.84 | ALDH1A1 (0.41) | MAPTTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL229536 | 0.84 | ALDH1A1 (0.41) | MAPTTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL1768448 | 0.82 | CYP3A4 (0.48) | TDP1DRD1CYP3A4KDM4EGAA | |
| Bromide SCHEMBL1033291 | 0.81 | ALDH1A1 (0.39) | MAPTTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL1622430 | 0.80 | TDP1 (0.46) | MAPTTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL1033292 | 0.79 | ALDH1A1 (0.37) | MAPTTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL25946762 | 0.79 | MAPT (0.44) | MAPTTDP1L3MBTL1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061439-A1 | CATALYTIC PHOSPHINATION METHOD | UNIVERSITE DE STRASBOURG (FR) | 2011-05-26 | — | — | WO | disclosed |