⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL13386456 | 0.98 | CA12 (0.57) | — | |
| Glycerin SCHEMBL6955459 | 0.85 | CA12 (0.46) | — | |
| Xylitol SCHEMBL6955597 | 0.82 | CA12 (0.44) | — | |
| SCHEMBL8320257 | 0.74 | CA12 (1.00) | — | |
| SCHEMBL17233960 | 0.73 | — | — | |
| SCHEMBL9332437 | 0.73 | — | — | |
| SCHEMBL2606749 | 0.73 | — | — | |
| SCHEMBL10924548 | 0.73 | TYR (0.50) | — | |
| SCHEMBL4442471 | 0.71 | — | — | |
| SCHEMBL15495276 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313305-A2 | Photoprotection compositions comprising chelating agents | THE PROCTER & GAMBLE COMPANY (US) | 1989-04-26 | — | — | EP | claimed |
| EP-0145228-A1 | Pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-06-19 | — | — | EP | claimed |
| US-20210395281-A1 | MACROCYCLIC CHELATES AND USES THEREOF | OXFORD FINANCE LLC | 2021-12-23 | — | — | US | disclosed |
| EP-3285583-B1 | SMALL MOLECULE INHIBITORS OF MCL-1 AND USES THEREOF | UNIV MICHIGAN REGENTS (US) | 2021-03-17 | — | — | EP | disclosed |
| US-10472362-B2 | Fused tricyclic imidazo pyrazines as modulators of TNF activity | UCB BIOPHARMA SPRL (BE) | 2019-11-12 | — | — | US | disclosed |
| EP-3125884-B1 | SMALL MOLECULE INHIBITORS OF MCL-1 AND USES THEREOF | UNIV MICHIGAN REGENTS (US) | 2019-11-06 | — | — | EP | disclosed |
| CN-109568652-A | Promote the dressing composition of wound healing | 粤肽生物科技(珠海)有限公司 | 2019-04-05 | — | — | CN | disclosed |
| US-20180222868-A1 | Indazole Derivatives as Modulators of TNF Activity | UCB PHARMA S.A. (BE) | 2018-08-09 | — | — | US | disclosed |
| US-20180222868-A1 | Indazole Derivatives as Modulators of TNF Activity | UCB PHARMA S.A. (BE) | 2018-08-09 | — | — | US | disclosed |
| US-10004737-B2 | Fused imidazole and pyrazole derivatives as modulators of TNF activity | UCB BIOPHARMA SPRL (BY) | 2018-06-26 | — | — | US | disclosed |
| US-9988383-B2 | Purine derivatives as modulators of TNF activity | UCB BIOPHARMA SPRL (BE) | 2018-06-05 | — | — | US | disclosed |
| CN-1072684-A | Cephalosporins derivatives | HOFFMANN LA ROCHE (CH) | 1993-06-02 | — | — | CN | disclosed |
| CN-1038814-A | Cephem compound and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1990-01-17 | — | — | CN | disclosed |
| US-4894455-A | Pharmaceutically active zinc complexes | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1990-01-16 | — | — | US | disclosed |
| US-4840958-A | Novel 3-hydroxypyrid-2-ones and 3-hydroxyprid-4-ones useful in treating patients having a toxic concentration of iron | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1989-06-20 | — | — | US | disclosed |
| US-4665064-A | IN BLOOD; ZINC CHELATE | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-05-12 | — | — | US | disclosed |
| EP-0093498-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING N-SUBSTITUTED-3-HYDROXYPYRID-2-ONE OR -4-ONE DERIVATIVES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-11-26 | — | — | EP | disclosed |
| US-4550101-A | Iron complexes of hydroxy pyridones useful for treating iron deficiency anemia | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-10-29 | — | — | US | disclosed |
| EP-0145228-A1 | Pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-06-19 | — | — | EP | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |