⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768217 | 0.73 | — | — | |
| SCHEMBL28151489 | 0.73 | — | — | |
| SCHEMBL15495276 | 0.73 | — | — | |
| SCHEMBL4442471 | 0.73 | — | — | |
| SCHEMBL10919191 | 0.69 | COMT (0.44) | — | |
| SCHEMBL17147384 | 0.69 | COMT (0.44) | — | |
| SCHEMBL7640934 | 0.69 | TYR (0.53) | — | |
| SCHEMBL6902004 | 0.67 | COMT (1.00) | — | |
| SCHEMBL4910334 | 0.67 | — | — | |
| SCHEMBL10924548 | 0.66 | TYR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260162-B | 3-Hydroxy-4-pyridone-ciprofloxacin coupling, preparation method and application thereof | 浙江大学 | 2024-07-05 | — | — | CN | disclosed |
| CN-115260162-A | 3-hydroxy-4-pyridone-ciprofloxacin coupling compound and preparation method and application thereof | 浙江大学 | 2022-11-01 | — | — | CN | disclosed |
| EP-0289002-B1 | Novel cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA (JP) | 1994-10-26 | — | — | EP | disclosed |
| EP-0315997-B1 | Cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA (JP) | 1994-04-20 | — | — | EP | disclosed |
| US-5075299-A | CEPHALOSPORIN COMPOUNDS AND ANTIBACTERIAL AGENTS | MEIJI SEIKA KAISHA, LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| US-5028601-A | Substituted with an amino thiazole group and a dihydroxy-pyridone group | MEIJI SAIKA KAISHA, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| US-4971961-A | ANTIBIOTICS AS BACTERICIDES AGAINST PSEUDOMONAS | MEIJI SEIKA KAISHA, LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0354576-A2 | Novel cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |
| EP-0315997-A2 | Cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA LTD. (JP) | 1989-05-17 | — | — | EP | disclosed |
| EP-0289002-A2 | Novel cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |