Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 9/20 | 0.36 |
| ▸ | PARN | O95453 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682211 | 0.81 | KMT2A (0.45) | — | |
| SCHEMBL17682308 | 0.80 | CNOT7 (0.39) | CNOT7PARNCYP11B2GRIN1GRIN2B | |
| SCHEMBL17682309 | 0.80 | CNOT7 (0.39) | CNOT7PARNCYP11B2GRIN1GRIN2B | |
| SCHEMBL17682279 | 0.71 | KMT2A (0.48) | — | |
| SCHEMBL17682280 | 0.71 | KMT2A (0.48) | — | |
| SCHEMBL17682249 | 0.71 | KMT2A (0.48) | — | |
| SCHEMBL19601312 | 0.70 | KMT2A (0.50) | — | |
| SCHEMBL9350776 | 0.70 | PDE4A (0.43) | CNOT7PARNJAK2JAK1JAK3 | |
| SCHEMBL27537551 | 0.69 | GRIN1 (0.43) | CNOT7PARNGRIN1GRIN2B | |
| SCHEMBL17682251 | 0.69 | KMT2A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016054971-A1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | 南京明德新药研发股份有限公司 | 2016-04-14 | — | — | WO | disclosed |