Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.59 |
| ▸ | ANPEP | P15144 | 4/20 | 0.53 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.53 |
| ▸ | DNPEP | Q9ULA0 | 3/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1769602 | 1.00 | SLC7A5 (0.59) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| SCHEMBL1769031 | 1.00 | SLC7A5 (0.59) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| SCHEMBL1769033 | 1.00 | SLC7A5 (0.59) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| SCHEMBL10928131 | 0.88 | DPP7 (0.54) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| SCHEMBL1277892 | 0.87 | ANPEP (0.68) | SLC7A5ANPEPRNPEPDNPEPDPP7 | |
| SCHEMBL1277891 | 0.87 | ANPEP (0.68) | SLC7A5ANPEPRNPEPDNPEPDPP7 | |
| SCHEMBL14067667 | 0.87 | ANPEP (0.68) | SLC7A5ANPEPRNPEPDNPEPDPP7 | |
| Bromide SCHEMBL7305048 | 0.85 | ANPEP (0.66) | SLC7A5ANPEPRNPEPDNPEPDPP7 | |
| Hydrochloric Acid SCHEMBL1277930 | 0.85 | ANPEP (0.66) | SLC7A5ANPEPRNPEPDNPEPDPP7 | |
| SCHEMBL7780961 | 0.85 | RNPEP (0.49) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501715-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVTY | Polyphor Ag (CH) | 2012-09-26 | — | — | EP | disclosed |
| WO-2011060937-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVTY | POLYPHOR AG (CH) | 2011-05-26 | — | — | WO | disclosed |