SCHEMBL14067667

SCHEMBL14067667

CC(C)CCNC(=O)[C@H](N)CC(C)C

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 5/20 0.68
RNPEP Q9H4A4 4/20 0.68
DNPEP Q9ULA0 4/20 0.68
SLC7A5 Q01650 1/20 0.48
DPP7 Q9UHL4 2/20 0.46
LAP3 P28838 3/20 0.45
CAPN9 O14815 1/20 0.44
CAPN1 P07384 1/20 0.44
CTSB P07858 1/20 0.44
MAPK1 P28482 1/20 0.44
RRM1 P23921 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1277892 1.00 ANPEP (0.68) ANPEPRNPEPDNPEPSLC7A5DPP7
SCHEMBL1277891 1.00 ANPEP (0.68) ANPEPRNPEPDNPEPSLC7A5DPP7
Hydrochloric Acid SCHEMBL1277930 0.98 ANPEP (0.66) ANPEPRNPEPDNPEPSLC7A5DPP7
Bromide SCHEMBL7305048 0.98 ANPEP (0.66) ANPEPRNPEPDNPEPSLC7A5DPP7
SCHEMBL1769033 0.87 SLC7A5 (0.59) ANPEPRNPEPDNPEPSLC7A5DPP7
SCHEMBL1769602 0.87 SLC7A5 (0.59) ANPEPRNPEPDNPEPSLC7A5DPP7
SCHEMBL1768387 0.87 SLC7A5 (0.59) ANPEPRNPEPDNPEPSLC7A5DPP7
SCHEMBL1769031 0.87 SLC7A5 (0.59) ANPEPRNPEPDNPEPSLC7A5DPP7
Bromide SCHEMBL7287179 0.86 ANPEP (0.57) ANPEPRNPEPDNPEPSLC7A5LAP3
SCHEMBL9113004 0.86 DPP7 (0.52) ANPEPRNPEPDNPEPSLC7A5DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080227806-A1 Novel Drugs for Dementia AMERICAN LIFE SCIENCE PHARMACEUTICALS (US) 2008-09-18 US disclosed
US-20080227806-A1 Novel Drugs for Dementia AMERICAN LIFE SCIENCE PHARMACEUTICALS (US) 2008-09-18 US disclosed
WO-2007038772-A1 NOVEL DRUGS FOR DEMENTIA AMERICAN LIFE SCIENCE PHARMACEUTICALS (US) 2007-04-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080227806-A1 Novel Drugs for Dementia CTSS, PRSS1, CBS ANPEP 89/4885RNPEP 209/4885DNPEP 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.