Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768399 | 1.00 | KDM4E (0.35) | KDM4EGFPT1KCNK3CSF1RCNR2 | |
| SCHEMBL1768963 | 0.87 | KDM4E (0.34) | KDM4EKCNK3CSF1RCNR2CNR1 | |
| SCHEMBL1768961 | 0.87 | KDM4E (0.34) | KDM4EKCNK3CSF1RCNR2CNR1 | |
| SCHEMBL1769360 | 0.79 | KDM4E (0.42) | KDM4EKCNK3KMT2ANPC1GAA | |
| SCHEMBL1769354 | 0.79 | KDM4E (0.42) | KDM4EKCNK3KMT2ANPC1GAA | |
| SCHEMBL1768572 | 0.77 | KDM4E (0.41) | KDM4EKMT2ANPC1GAARAB9A | |
| SCHEMBL1768574 | 0.77 | KDM4E (0.41) | KDM4EKMT2ANPC1GAARAB9A | |
| SCHEMBL1769647 | 0.76 | PSEN1 (0.33) | KDM4ECSF1RCNR2CNR1 | |
| SCHEMBL22135151 | 0.73 | KDM4E (0.40) | KDM4EKCNK3CNR2CNR1KMT2A | |
| SCHEMBL13584959 | 0.71 | PSEN1 (0.34) | KDM4ECSF1RCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501715-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVTY | Polyphor Ag (CH) | 2012-09-26 | — | — | EP | disclosed |
| WO-2011060937-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVTY | POLYPHOR AG (CH) | 2011-05-26 | — | — | WO | disclosed |