Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768961 | 0.79 | KDM4E (0.34) | KDM4ECHRNB2CHRNB4CHRNA4CNR2 | |
| SCHEMBL22135150 | 0.79 | LMNA (0.47) | KDM4EHSD17B10ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL1768963 | 0.79 | KDM4E (0.34) | KDM4ECHRNB2CHRNB4CHRNA4CNR2 | |
| SCHEMBL22135161 | 0.78 | ALDH1A1 (0.34) | KDM4ECHRNB2CHRNB4CHRNA4ALDH1A1 | |
| SCHEMBL22135145 | 0.76 | NAMPT (0.38) | KDM4EPIK3CDCNR2CNR1ALDH1A1 | |
| SCHEMBL22135155 | 0.76 | PIK3CD (0.41) | PIK3CDHSD17B10CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL29306397 | 0.74 | HSD17B10 (0.48) | KDM4EPIK3CDHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL1768397 | 0.73 | KDM4E (0.35) | KDM4ECNR2CNR1GAARAB9A | |
| SCHEMBL1768399 | 0.73 | KDM4E (0.35) | KDM4ECNR2CNR1GAARAB9A | |
| SCHEMBL22135163 | 0.72 | HSD17B10 (0.38) | PIK3CDHSD17B10CHRNB2CHRNB4CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132566-A1 | STING PYRAZOLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |