Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.50 |
| ▸ | IKBKB | O14920 | 2/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | AKT2 | P31751 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.47 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12751291 | 0.82 | IKBKB (0.51) | NFE2L2IKBKBRAF1RPS6KB1MAPK1 | |
| SCHEMBL13504087 | 0.82 | IKBKB (0.51) | NFE2L2IKBKBRAF1RPS6KB1MAPK1 | |
| SCHEMBL17684676 | 0.80 | IKBKB (0.45) | NFE2L2IKBKBRAF1RPS6KB1MAPK1 | |
| Hydrochloric Acid SCHEMBL6979971 | 0.80 | IKBKB (0.50) | NFE2L2IKBKBRAF1RPS6KB1MAPK1 | |
| SCHEMBL13504005 | 0.79 | MAPT (0.45) | NFE2L2IKBKBRAF1RPS6KB1MAPK1 | |
| SCHEMBL23842730 | 0.77 | IKBKB (0.65) | NFE2L2IKBKBRAF1RPS6KB1MAPK1 | |
| Hydrochloric Acid SCHEMBL23830744 | 0.75 | IKBKB (0.62) | NFE2L2IKBKBRAF1RPS6KB1MAPK1 | |
| SCHEMBL13503573 | 0.75 | MAPT (0.46) | NFE2L2IKBKBRAF1RPS6KB1MAPK1 | |
| SCHEMBL13504103 | 0.75 | IGF1R (0.42) | NFE2L2IKBKBRAF1RPS6KB1MAPK1 | |
| SCHEMBL3438486 | 0.75 | IKBKB (0.57) | NFE2L2IKBKBRAF1RPS6KB1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160130278-A1 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2016-05-12 | — | — | US | disclosed |
| EP-3009421-A1 | GLYCINE TRANSPORTER INHIBITOR | Taisho Pharmaceutical Co., Ltd. (JP) | 2016-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130278-A1 | GLYCINE TRANSPORTER INHIBITOR | SLC1A2, SLC6A5, SLC18A2 | NFE2L2 1980/4885IKBKB 2164/4885RAF1 4484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.