Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17685170 | 0.91 | SLC6A4 (0.31) | SLC6A4SLC6A3TP53MAPT | |
| SCHEMBL17685053 | 0.88 | MAPT (0.42) | TP53MAPTLMNATHRB | |
| SCHEMBL3105744 | 0.86 | S1PR1 (0.35) | SLC6A4SLC6A3TP53MAPTBRD4 | |
| SCHEMBL17685215 | 0.86 | TP53 (0.36) | TP53MAPTLMNATHRB | |
| SCHEMBL17685131 | 0.84 | — | — | |
| SCHEMBL17685139 | 0.80 | MAPT (0.44) | TP53MAPTLMNATHRB | |
| SCHEMBL17685231 | 0.80 | MAPT (0.41) | TP53MAPTLMNATHRB | |
| SCHEMBL17685187 | 0.79 | MAPT (0.40) | TP53MAPTLMNATHRB | |
| SCHEMBL2988858 | 0.76 | MAPT (0.41) | TP53MAPTLMNATHRB | |
| SCHEMBL17685211 | 0.76 | MAPT (0.56) | TP53MAPTLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2813498-B1 | Compounds for Alzheimer's disease | MANFREDI JOHN (US) | 2016-04-20 | — | — | EP | claimed |