⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30123403 | 0.75 | KDM4E (0.31) | — | |
| SCHEMBL3743518 | 0.75 | KDM4E (0.31) | — | |
| SCHEMBL5640922 | 0.72 | — | — | |
| SCHEMBL1091555 | 0.72 | — | — | |
| SCHEMBL15846496 | 0.71 | ALDH1A1 (0.30) | — | |
| SCHEMBL19483162 | 0.68 | TDP1 (0.35) | — | |
| SCHEMBL735831 | 0.67 | HSD17B10 (0.42) | — | |
| SCHEMBL14851716 | 0.67 | — | — | |
| SCHEMBL18258606 | 0.67 | HSD17B10 (0.42) | — | |
| SCHEMBL4623112 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12629343-B2 | Multi-layer transdermal drug delivery system containing ibuprofen or structural analogue thereof | Demotech, Inc. (CN) | 2026-05-19 | — | — | US | claimed |
| US-20220008351-A1 | MULTI-LAYER TRANSDERMAL DRUG DELIVERY SYSTEM CONTAINING IBUPROFEN OR STRUCTURAL ANALOGUE THEREOF | Demotech, Inc. (CN) | 2022-01-13 | — | — | US | claimed |
| EP-3900710-A1 | MULTI-LAYER TRANSDERMAL DRUG DELIVERY SYSTEM CONTAINING IBUPROFEN OR STRUCTURAL ANALOGUE THEREOF | Demotech. Inc. (CN) | 2021-10-27 | — | — | EP | claimed |
| CN-112206222-A | Multi-layer transdermal drug delivery system containing ibuprofen structural analogs | 北京德默高科医药技术有限公司 | 2021-01-12 | — | — | CN | claimed |
| CN-109432061-B | Multi-layer transdermal delivery system containing ibuprofen or structural analogs thereof | 北京德默高科医药技术有限公司 | 2020-10-30 | — | — | CN | claimed |
| US-7968507-B2 | Composition for stripping and stripping method | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-06-28 | — | — | US | claimed |
| US-20090084406-A1 | Composition for stripping and stripping method | SAMSUNG ELECTRONICS CO., LTD. | 2009-04-02 | — | — | US | claimed |
| CN-101398639-A | Composition for stripping and stripping method | SAMSUNG ELECTRONICS CO LTD (KR) | 2009-04-01 | — | — | CN | claimed |
| EP-0531837-A1 | Fungicidal mixtures | BASF Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | claimed |
| US-12629343-B2 | Multi-layer transdermal drug delivery system containing ibuprofen or structural analogue thereof | Demotech, Inc. (CN) | 2026-05-19 | — | — | US | disclosed |
| WO-2023119175-A1 | NEW REINFORCING ORGANIC FILLERS FOR ELASTOMERIC COMPOUNDS AND TYRES THAT COMPRISE THEM | PIRELLI TYRE S.P.A. (IT) | 2023-06-29 | — | — | WO | disclosed |
| CN-112111135-B | Conductive polylactic resin composition and preparation method thereof | 浙江海正生物材料股份有限公司 | 2022-10-18 | — | — | CN | disclosed |
| US-11230534-B2 | KDM1A inhibitors for the treatment of disease | IMAGO BIOSCIENCES, INC. (US) | 2022-01-25 | — | — | US | disclosed |
| US-20220008351-A1 | MULTI-LAYER TRANSDERMAL DRUG DELIVERY SYSTEM CONTAINING IBUPROFEN OR STRUCTURAL ANALOGUE THEREOF | Demotech, Inc. (CN) | 2022-01-13 | — | — | US | disclosed |
| US-4775519-A | CONTACTING WITH COUNTERCURRENT STREAM OF AQUEOUS N-METHYLDIETHANOLAMINE AND IMIDAZOLE | TEXACO INC. (US) | 1988-10-04 | — | — | US | disclosed |
| US-4696803-A | METHYLDIETHANOLAMINE DIETHYLHYDROXYLAMINE | TEXACO INC. (US) | 1987-09-29 | — | — | US | disclosed |
| EP-0000649-B1 | 5-SUBSTITUTED-1,2-DIHYDRO-3H-PYRROLO(1,2-A)PYRROLE-1-CARBONITRILES AND PROCESS FOR THEIR CONVERSION TO THE CORRESPONDING 1-CARBOXYLIC ACIDS | SYNTEX (U.S.A.) INC. (US) | 1981-03-25 | — | — | EP | disclosed |
| US-4232038-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, AND MUSCLE RELAXANTS | SYNTEX (U.S.A.) INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-4140698-A | 1,2-Dihydro-3H-pyrrolo[1,2-a]pyrrole-1-nitriles | SYNTEX (USA) INC. (US) | 1979-02-20 | — | — | US | disclosed |
| EP-0000649-A1 | 5-substituted-1,2-dihydro-3H-pyrrolo(1,2-a)pyrrole-1-carbonitriles and process for their conversion to the corresponding 1-carboxylic acids | SYNTEX (U.S.A.) INC. (US) | 1979-02-07 | — | — | EP | disclosed |