SCHEMBL176853

SCHEMBL176853

CCCCCC(O)P(=O)(O)O

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDPS P14324 5/20 0.64
LAP3 P28838 2/20 0.59
S1PR2 O95136 5/20 0.52
S1PR1 P21453 5/20 0.52
S1PR3 Q99500 5/20 0.52
S1PR4 O95977 4/20 0.52
SMPD1 P17405 3/20 0.50
LPAR3 Q9UBY5 3/20 0.50
LPAR2 Q9HBW0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5745776 1.00 FDPS (0.64) FDPSLAP3S1PR2S1PR1S1PR3
SCHEMBL2251269 0.98 FDPS (0.65) FDPSLAP3S1PR2S1PR1S1PR3
SCHEMBL2254762 0.98 FDPS (0.65) FDPSLAP3S1PR2S1PR1S1PR3
SCHEMBL2255133 0.98 FDPS (0.65) FDPSLAP3S1PR2S1PR1S1PR3
SCHEMBL629521 0.98 FDPS (0.65) FDPSLAP3S1PR2S1PR1S1PR3
SCHEMBL10876126 0.98 FDPS (0.65) FDPSLAP3S1PR2S1PR1S1PR3
SCHEMBL2250970 0.98 FDPS (0.65) FDPSLAP3S1PR2S1PR1S1PR3
SCHEMBL2254314 0.98 FDPS (0.65) FDPSLAP3S1PR2S1PR1S1PR3
SCHEMBL1259333 0.98 FDPS (0.65) FDPSLAP3S1PR2S1PR1S1PR3
SCHEMBL6433185 0.98 FDPS (0.65) FDPSLAP3S1PR2S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118847375-A Flotation reagent and method for carrying out flotation separation on micro-fine cassiterite and magnesium-containing gangue minerals 中南大学 2024-10-29 CN claimed
CN-118847375-A Flotation reagent and method for carrying out flotation separation on micro-fine cassiterite and magnesium-containing gangue minerals 中南大学 2024-10-29 CN disclosed
US-20120108533-A1 NOVEL PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D (BE) 2012-05-03 US disclosed
EP-2424874-A1 NOVEL PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL ANGENTS Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) 2012-03-07 EP disclosed
WO-2010125200-A1 NOVEL PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL ANGENTS KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) 2010-11-04 WO disclosed
EP-0826652-B1 PROCESS FOR PREPARING ASYMMETRIC COMPOUND BY USING METAL COMPLEX NAGASE & CO LTD (JP) 2006-09-06 EP disclosed
US-6090969-A REACTING AN OPTICALLY ACTIVE BINAPHTHOL WITH AN ALKALI METAL ALUMINUM HYDRIDE OR A DIALKYLALUMINUM HYDRIDE AND AN ALKALI OR ALKALINE EARTH METAL BASE NAGASE AND CO., LTD. (JP) 2000-07-18 US disclosed
US-5847186-A Process for preparing asymmetric compound by using metal complex NAGASE & COMPANY, LTD. (JP) 1998-12-08 US disclosed
CN-1182412-A Process for preparing asymmetric compound by using metal complex NAGASE & CO LTD (JP) 1998-05-20 CN disclosed
EP-0826652-A1 PROCESS FOR PREPARING ASYMMETRIC COMPOUND BY USING METAL COMPLEX NAGASE & COMPANY, LTD. (JP) 1998-03-04 EP disclosed
EP-0412387-B1 Diarylacetylenes, their process and use BASF AG (DE) 1993-11-24 EP disclosed
US-5256694-A For skin disorders; carcinomas BASF AKTIENGESELLSCHAFT (DE) 1993-10-26 US disclosed
US-5126371-A Precancerous skin conditions, acne, psoriasis BASF AKTEINGESELLSCHAFT (DE) 1992-06-30 US disclosed
US-5087637-A Skin disorders BASF AKTIENGESELLSCHAFT (DE) 1992-02-11 US disclosed
US-4994489-A Ester derivatives of diarylacetylenes, their compositions and their use in acne treatment BASF AKTIENGESELLSCHAFT 1991-02-19 US disclosed
EP-0412387-A2 Diarylacetylenes, their process and use BASF Aktiengesellschaft (DE) 1991-02-13 EP disclosed
EP-0176034-B1 DIARYL ACETYLENES, THEIR PREPARATION AND USE BASF Aktiengesellschaft (DE) 1989-08-30 EP disclosed
US-4806558-A Diarylacetylenes and their use in treating acne BASF AKTIENGESELLSCHAFT (DE) 1989-02-21 US disclosed
EP-0176034-A2 Diaryl acetylenes, their preparation and use BASF Aktiengesellschaft (DE) 1986-04-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108533-A1 NOVEL PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS PNP, TYMP, MTAP FDPS 930/4885LAP3 2319/4885S1PR2 954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.