Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247934 | 1.00 | — | — | |
| SCHEMBL9242233 | 1.00 | TSHR (0.42) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL7062919 | 0.89 | — | — | |
| SCHEMBL6585416 | 0.77 | — | — | |
| SCHEMBL3265077 | 0.75 | TSHR (0.41) | TSHRTHRBDNM1KMT2AALDH1A1 | |
| SCHEMBL3507116 | 0.74 | — | — | |
| SCHEMBL5586092 | 0.74 | TSHR (0.42) | TSHRTHRBDNM1ALDH1A1EPHX1 | |
| SCHEMBL9451397 | 0.74 | TSHR (0.42) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL22438694 | 0.74 | TSHR (0.42) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL2018319 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2520640-B1 | LUBRICATING OIL COMPOSITION | IDEMITSU KOSAN CO (JP) | 2016-04-20 | — | — | EP | claimed |