Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 6/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 7/20 | 0.36 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2018319 | 1.00 | — | — | |
| SCHEMBL7611194 | 1.00 | TSHR (0.42) | TSHRTHRBCES2CTSLCTSB | |
| SCHEMBL7613233 | 1.00 | TSHR (0.42) | TSHRTHRBCES2CTSLCTSB | |
| SCHEMBL5481202 | 1.00 | TSHR (0.42) | TSHRTHRBCES2CTSLCTSB | |
| SCHEMBL2025361 | 0.97 | — | — | |
| SCHEMBL6706888 | 0.87 | FAAH (0.52) | GMNNTP53POLBMAPTCYP2C9 | |
| SCHEMBL2018589 | 0.77 | — | — | |
| SCHEMBL3265077 | 0.75 | TSHR (0.41) | TSHRTHRBCES2CTSLCTSB | |
| SCHEMBL3507116 | 0.74 | — | — | |
| SCHEMBL9451397 | 0.74 | TSHR (0.42) | TSHRTHRBCES2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294369-B2 | Polymerisable cinnamates with lateral substitution | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2007-11-13 | — | — | US | disclosed |
| EP-1524308-B1 | Polymerisable Cinnamates with lateral substitution | MERCK PATENT GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |
| US-20050227021-A1 | Polymerisable cinnamates with lateral substitution | MERCK PATENT GMBH (DE) | 2005-10-13 | — | — | US | disclosed |
| EP-1524308-A1 | Polymerisable Cinnamates with lateral substitution | MERCK PATENT GmbH (DE) | 2005-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227021-A1 | Polymerisable cinnamates with lateral substitution | VIM, TYR, LAGE3 | TSHR 2027/4885THRB 2737/4885CES2 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.