Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2287082 | 0.72 | PDCD1 (0.35) | MAPK1PDCD1CD274 | |
| SCHEMBL17709510 | 0.71 | ALDH1A1 (0.71) | MAPK1ALDH1A1RAB9ANPC1TP53 | |
| SCHEMBL1768503 | 0.69 | ALDH1A1 (0.36) | MAPK1ALDH1A1RAB9ANPC1TP53 | |
| SCHEMBL12489603 | 0.69 | ALDH1A1 (0.83) | MAPK1ALDH1A1RAB9ANPC1TP53 | |
| SCHEMBL19058265 | 0.68 | AHR (0.53) | MAPK1ALDH1A1RAB9ANPC1TP53 | |
| SCHEMBL10714421 | 0.67 | ALDH1A1 (0.52) | MAPK1ALDH1A1RAB9ANPC1TP53 | |
| SCHEMBL9762542 | 0.66 | ALDH1A1 (0.70) | MAPK1ALDH1A1RAB9ANPC1TP53 | |
| SCHEMBL29687904 | 0.66 | ALDH1A1 (0.70) | MAPK1ALDH1A1RAB9ANPC1TP53 | |
| SCHEMBL19107130 | 0.66 | MAPK1 (0.70) | MAPK1ALDH1A1RAB9ANPC1TP53 | |
| SCHEMBL29671005 | 0.66 | ALDH1A1 (0.62) | MAPK1ALDH1A1RAB9ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061439-A1 | CATALYTIC PHOSPHINATION METHOD | UNIVERSITE DE STRASBOURG (FR) | 2011-05-26 | — | — | WO | disclosed |